Very easy !!
You need any kernel that supports FTDI , I use any of the
http://sheeva.with-linux.com/sheeva/Kernels.
After that you can use python with commands like :-
self = serial.Serial('/dev/ttyUSB2', 19200, timeout=10)
write_this = 'what you want to send'
self.write(write_this)
data = self.readline().strip()
print data